Insidepenton Com Images Generator Harvest Small

Purdue implantable oxygen generator harvests power from externally applied ultrasonics

Sept. 29, 2011
Purdue University researchers have devised miniature transducers that are implanted in tumors to generate oxygen, boosting the killing power of radiation and chemotherapy.

Resources:
Birck Nanotechnology Center
Transactions on Biomedical Engineering

Purdue University researchers have devised miniature transducers that are implanted in tumors to generate oxygen, boosting the killing power of radiation and chemotherapy treatments. The devices get electrical power from ultrasonic waves beamed at them from outside the patient’s body.

The technology is designed to treat solid tumors that have little oxygen at their cores. Radiation therapy needs oxygen to be effective, so such tumors, which characterize pancreatic, cervical, and liver cancers, have proven hard to treat.

Purdue’s implantable micro oxygen generator harvests energy from an incoming 2.15-MHz ultrasonic wave using a lead-zirconate-titanate (PZT) transducer. Electrical energy from the PZT transducer is rectified to a dc voltage that is then applied to the water in the interstitial fluid through a set of interdigitated electrodes. This separates oxygen and hydrogen in the water in a chemical process called electrolysis.

The oxygen generators were created at Purdue’s Birck Nanotechnology Center. Researchers have tested the devices in pancreatic tumors implanted in mice, showing they generated oxygen, which led to the tumors shrinking faster under treatment. The devices are slightly less than 1-cm long and are inserted into tumors with hypodermic biopsy needles.

Findings are detailed in a research paper appearing online in Transactions on Biomedical Engineering. The paper was written by research assistant professor Teimour Maleki, doctoral students Ning Cao and Seung Hyun Song, Indiana University School of Medicine assistant professor of clinical radiation oncology Song-Chu (Arthur) Ko, and professor of electrical and computer engineering and biomedical engineering Babak Ziaie.

© 2011 Penton Media, Inc.

Sponsored Recommendations

From concept to consumption: Optimizing success in food and beverage

April 9, 2024
Identifying opportunities and solutions for plant floor optimization has never been easier. Download our visual guide to quickly and efficiently pinpoint areas for operational...

A closer look at modern design considerations for food and beverage

April 9, 2024
With new and changing safety and hygiene regulations at top of mind, its easy to understand how other crucial aspects of machine design can get pushed aside. Our whitepaper explores...

Cybersecurity and the Medical Manufacturing Industry

April 9, 2024
Learn about medical manufacturing cybersecurity risks, costs, and threats as well as effective cybersecurity strategies and essential solutions.

Condition Monitoring for Energy and Utilities Assets

April 9, 2024
Condition monitoring is an essential element of asset management in the energy and utilities industry. The American oil and gas, water and wastewater, and electrical grid sectors...

Voice your opinion!

To join the conversation, and become an exclusive member of Machine Design, create an account today!